The 6.2-mile course is a scenic tour through Boston's Back Bay. Notable neighborhoods and attractions include the legendary Bull and Finch Pub, after which the television series "Cheers" was developed, the campus of Boston University, and trendy Kenmore Square. The race begins on Charles Street, winds down picturesque Commonwealth Avenue and Bay State Road as far west as Babcock Street near Boston University, before heading back on Commonwealth Avenue, around the Public Garden, and finishing on Charles Street.

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